Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 3/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743962 | 0.90 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EALDH1A1NLRP1 | |
| SCHEMBL5742298 | 0.86 | KMT2A (0.51) | MEN1KMT2AKDM4EALDH1A1NLRP1 | |
| SCHEMBL5629297 | 0.83 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1NLRP1 | |
| SCHEMBL5629311 | 0.83 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1NLRP1 | |
| SCHEMBL5741743 | 0.80 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1NLRP1 | |
| SCHEMBL5630106 | 0.79 | HRH3 (0.46) | MEN1KMT2AKDM4EALDH1A1NLRP1 | |
| SCHEMBL5630092 | 0.79 | HRH3 (0.46) | MEN1KMT2AKDM4EALDH1A1NLRP1 | |
| SCHEMBL8546624 | 0.78 | TDP1 (0.41) | KMT2AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL5688378 | 0.78 | TDP1 (0.41) | KMT2AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL5628828 | 0.77 | OPRL1 (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | claimed |