Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14451949 | 0.90 | KDR (0.41) | KDRMAPK14 | |
| SCHEMBL5738887 | 0.84 | KDR (0.46) | KDRMAPK14 | |
| SCHEMBL5740276 | 0.83 | KDR (0.43) | KDRMAPK14 | |
| SCHEMBL4045183 | 0.83 | KDR (0.61) | KDRMAPK14 | |
| SCHEMBL27888121 | 0.80 | KDR (0.47) | KDRMAPK14 | |
| SCHEMBL5741796 | 0.80 | KDR (0.44) | KDRMAPK14 | |
| SCHEMBL5740473 | 0.80 | MAP2K1 (0.52) | KDRMAPK14 | |
| SCHEMBL5739638 | 0.79 | KDR (0.48) | KDRMAPK14 | |
| SCHEMBL5740103 | 0.79 | KDR (0.59) | KDRMAPK14 | |
| SCHEMBL5739989 | 0.78 | KDR (0.53) | KDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183033-B1 | PYRROLOTRIAZINE INHIBITORS OF KINASES | BRISTOL MYERS SQUIBB CO (US) | 2006-03-01 | — | — | EP | claimed |