Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.67 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939162 | 0.87 | OXTR (0.73) | OXTRAVPR1AHTR1AHTR1BHTR2A | |
| SCHEMBL4944329 | 0.87 | OXTR (0.73) | OXTRAVPR1AHTR1AHTR1BHTR2A | |
| SCHEMBL4943696 | 0.86 | OXTR (0.72) | OXTRAVPR1ALMNAMMP1MMP3 | |
| SCHEMBL4942110 | 0.85 | OXTR (0.71) | OXTRAVPR1ALMNAMMP1MMP3 | |
| SCHEMBL7164251 | 0.84 | OXTR (0.70) | OXTRAVPR1AHTR1AHTR1BHTR2A | |
| SCHEMBL4939792 | 0.84 | OXTR (0.70) | OXTRAVPR1AHTR1AHTR1BHTR2A | |
| SCHEMBL7086637 | 0.84 | OXTR (0.70) | OXTRAVPR1ALMNAMMP1MMP3 | |
| SCHEMBL4943384 | 0.84 | OXTR (0.70) | OXTRAVPR1AHTR1AHTR1BHTR2A | |
| SCHEMBL7088615 | 0.84 | OXTR (0.70) | OXTRAVPR1AHTR1AHTR1BHTR2A | |
| SCHEMBL4942292 | 0.84 | OXTR (0.70) | OXTRAVPR1ALMNAMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | disclosed |