SCHEMBL5742834

SCHEMBL5742834

CC(C)(C)OC(=O)NCC(CO)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.50
CTSS P25774 3/20 0.50
SYK P43405 1/20 0.50
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
ATM Q13315 1/20 0.44
MALT1 Q9UDY8 1/20 0.43
IDO1 P14902 1/20 0.43
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
KDM4A O75164 1/20 0.42
MAPT P10636 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4000452 0.90 MMP13 (0.46) CTSKCTSSSYKATMMALT1
SCHEMBL7837084 0.87 SYK (0.43) CTSKCTSSSYKMALT1MEN1
SCHEMBL1429047 0.87 CTSK (0.49) CTSKCTSSSYKMTNR1AMTNR1B
SCHEMBL16680112 0.87 MAPT (0.54) CTSKCTSSSYKMTNR1AMTNR1B
SCHEMBL6592966 0.87 CTSK (0.49) CTSKCTSSSYKMTNR1AMTNR1B
SCHEMBL4583612 0.87 MAPT (0.54) CTSKCTSSSYKMTNR1AMTNR1B
SCHEMBL16897058 0.87 CTSK (0.49) CTSKCTSSSYKMTNR1AMTNR1B
SCHEMBL7825061 0.87 SYK (0.43) CTSKCTSSSYKMALT1MEN1
SCHEMBL1241387 0.86 AAK1 (0.46) CTSKCTSSSYKMAPT
SCHEMBL16798314 0.86 SYK (0.48) CTSKCTSSSYKMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021044230-A1 PROCESS FOR THE SYNTHESIS OF THE SODIUM SALT OF 4-[[(LR)-2-[5-(2-FLUORO-3-METHOXYPHENYL)-3-[[2-FLUORO-6-(TRIFLUOROMETHYL)-PHENYL]METHYL]-3,6-DIHYDRO-4-METHYL-2,6-DIOXO-L(2H)-PYRIMIDINYL]-L- PHENYLETHYL]AMINO]-BUTANOIC ACID (ELAGOLIX SODIUM SALT) AND INTERMEDIATES OF SAID PROCESS INDUSTRIALE CHIMICA S.R.L. (IT) 2021-03-11 WO disclosed
EP-1620432-A1 NK-2 ANTAGONIST BASIC LINEAR COMPOUNDS AND FORMULATIONS CONTAINING THEM Menarini Ricerche S.p.A. (IT) 2006-02-01 EP disclosed
WO-2004094412-A1 NK-2 ANTAGONIST BASIC LINEAR COMPOUNDS AND FORMULATIONS CONTAINING THEM MENARINI RICERCHE S.P.A. (IT) 2004-11-04 WO disclosed
CN-1160329-C O-thiocarbamoyl-aminoalkanol compounds, pharmaceutically acceptable salts thereof and process for preparing the same SK株式会社 2004-08-04 CN disclosed
EP-1149076-B1 O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME SK CORP (KR) 2003-10-22 EP disclosed
CN-1346346-A O-thiocarbamoyl-aminoalkanol compounds, pharmaceutically acceptable salts thereof and process for preparing the same SK CORP (KR) 2002-04-24 CN disclosed
EP-1149076-A1 O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME SK Corporation (KR) 2001-10-31 EP disclosed
WO-2000046191-A1 O-THIOCARBAMOYL-AMINOALKANOL COMPOUNDS, THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR PREPARING THE SAME SK CORPORATION (KR) 2000-08-10 WO disclosed
US-5935997-A O-thiocarbamoyl-aminoalkanol compounds, their pharmaceutically useful salts and process for preparing the same YUKONG LIMITED (KR) 1999-08-10 US disclosed