Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485271 | 0.83 | BUB1 (0.34) | BUB1 | |
| SCHEMBL5485267 | 0.83 | BUB1 (0.34) | BUB1 | |
| SCHEMBL751694 | 0.79 | BUB1 (0.35) | BUB1 | |
| SCHEMBL4255398 | 0.78 | BUB1 (0.32) | BUB1 | |
| SCHEMBL28543041 | 0.73 | CTSK (0.34) | — | |
| SCHEMBL4185350 | 0.70 | USP2 (0.43) | — | |
| SCHEMBL992886 | 0.69 | USP2 (0.39) | — | |
| SCHEMBL1839800 | 0.69 | GRIN2B (0.38) | — | |
| SCHEMBL6017594 | 0.67 | AVPR1A (0.55) | — | |
| SCHEMBL20054876 | 0.67 | GRIN2B (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | disclosed |