Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.62 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | TPH1 | P17752 | 2/20 | 0.56 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.54 |
| ▸ | CTSC | P53634 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700701 | 1.00 | NAMPT (0.62) | NAMPTSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL11425334 | 0.91 | SLC7A5 (0.57) | NAMPTSLC7A5ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL7268206 | 0.88 | NAMPT (0.58) | NAMPTSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL17844273 | 0.88 | ALPI (0.68) | NAMPTSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL7698097 | 0.87 | LNPEP (0.60) | LTA4HALDH1A1 | |
| SCHEMBL31746131 | 0.86 | ECE1 (0.58) | NAMPTALPIALDH1A1 | |
| SCHEMBL10898440 | 0.86 | SLC7A5 (0.53) | NAMPTSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL14493298 | 0.86 | ECE1 (0.58) | NAMPTALPIALDH1A1 | |
| SCHEMBL903518 | 0.85 | TACR1 (0.57) | NAMPTSLC7A5ALPIPKMPTGS1 | |
| SCHEMBL28056454 | 0.85 | TACR1 (0.57) | NAMPTSLC7A5ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | claimed |
| CN-113226377-B | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2022-10-18 | — | — | CN | disclosed |