Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 6/20 | 0.55 |
| ▸ | LAP3 | P28838 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743374 | 0.87 | NAMPT (0.62) | ALDH1A1LTA4H | |
| SCHEMBL7700701 | 0.87 | NAMPT (0.62) | ALDH1A1LTA4H | |
| SCHEMBL27386689 | 0.84 | LTA4H (0.65) | LNPEPLTA4HLAP3PPARGPPARA | |
| SCHEMBL11425334 | 0.84 | SLC7A5 (0.57) | LNPEP | |
| SCHEMBL7281929 | 0.83 | MMP9 (0.63) | LNPEPLTA4HLAP3PPARGMAOB | |
| Hydrochloric Acid SCHEMBL27315039 | 0.82 | MMP9 (0.62) | LNPEPLTA4HLAP3PPARGMAOB | |
| Hydrochloric Acid SCHEMBL10350044 | 0.82 | MMP9 (0.62) | LNPEPLTA4HLAP3PPARGMAOB | |
| SCHEMBL7698099 | 0.82 | LNPEP (0.59) | LNPEPLTA4HLAP3 | |
| SCHEMBL288912 | 0.81 | SLC7A5 (0.69) | LTA4HLAP3PPARGMAOBPARP10 | |
| SCHEMBL515522 | 0.81 | SLC7A5 (0.69) | LTA4HLAP3PPARGMAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |