Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 6/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5742707 | 0.94 | AGPAT2 (0.49) | AGPAT2PTGS1PTGS2BACE1XDH | |
| SCHEMBL5742899 | 0.93 | AGPAT2 (0.55) | AGPAT2PTGS1PTGS2OPRL1BACE1 | |
| SCHEMBL5740861 | 0.91 | MAPT (0.48) | AGPAT2OPRL1XDHACP1TP53 | |
| SCHEMBL5742913 | 0.91 | KMT2A (0.43) | AGPAT2PTGS1PTGS2XDHACP1 | |
| SCHEMBL5741129 | 0.88 | DOT1L (0.51) | OPRL1MAPT | |
| SCHEMBL5743131 | 0.87 | BACE1 (0.50) | AGPAT2PTGS1PTGS2BACE1TP53 | |
| SCHEMBL5742115 | 0.86 | DHODH (0.40) | AGPAT2PTGS1PTGS2XDHTP53 | |
| SCHEMBL5742375 | 0.85 | MAPT (0.51) | AGPAT2BACE1ACP1TP53MAPT | |
| SCHEMBL5743033 | 0.85 | MCHR1 (0.47) | AGPAT2OPRL1ACP1 | |
| SCHEMBL5743347 | 0.85 | AGPAT2 (0.57) | AGPAT2ACP1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |