Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907052 | 0.84 | TP53 (0.43) | TP53CYP3A4NQO1LTA4HLMNA | |
| 1,3-Diethoxybenzene SCHEMBL1100167 | 0.84 | TP53 (0.71) | TP53CYP3A4NQO1LTA4HLMNA | |
| SCHEMBL8552100 | 0.83 | KMT2A (0.59) | LMNAMAPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4187873 | 0.82 | TSHR (0.54) | LTA4HCYP1A2CYP2C19SMN1; SMN2THRB | |
| SCHEMBL22345190 | 0.80 | APP (0.43) | TP53CYP3A4ALDH1A1SMN1; SMN2APP | |
| SCHEMBL21177828 | 0.80 | APP (0.43) | TP53CYP3A4ALDH1A1SMN1; SMN2APP | |
| SCHEMBL3657469 | 0.79 | APP (0.46) | TP53CYP3A4LMNAMAPK1CYP1A2 | |
| SCHEMBL30500239 | 0.79 | APP (0.46) | TP53CYP3A4LMNAMAPK1CYP1A2 | |
| SCHEMBL25169961 | 0.79 | TSHR (0.65) | LTA4HTHRBKMT2ANR1H4TSHR | |
| SCHEMBL25167623 | 0.79 | TSHR (0.65) | LTA4HTHRBKMT2ANR1H4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266410-A | A kind of 8 epi puupehedione synthetic method | 哈尔滨工业大学（威海） | 2017-10-20 | — | — | CN | claimed |
| CN-106083803-A | A kind of synthetic method of marine natural products Puupehedione | 哈尔滨工业大学（威海） | 2016-11-09 | — | — | CN | claimed |
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | VALO HEALTH, INC. | 2023-11-02 | — | — | US | disclosed |
| US-11518833-B2 | Composition, film, near infrared cut filter, laminate, pattern forming method, solid image pickup element, image display device, infrared sensor, and color filter | FUJIFILM CORPORATION (JP) | 2022-12-06 | — | — | US | disclosed |
| US-11209582-B2 | Composition, curable composition, cured film, near infrared cut filter, infrared transmitting filter, solid image pickup element, infrared sensor, and camera module | FUJIFILM CORPORATION (JP) | 2021-12-28 | — | — | US | disclosed |
| US-11118059-B2 | Film, film forming method, optical filter, laminate, solid image pickup element, image display device, and infrared sensor | FUJIFILM CORPORATION (JP) | 2021-09-14 | — | — | US | disclosed |
| US-20210139708-A1 | COMPOSITION, FILM, NEAR INFRARED CUT FILTER, LAMINATE, PATTERN FORMING METHOD, SOLID IMAGE PICKUP ELEMENT, IMAGE DISPLAY DEVICE, INFRARED SENSOR, AND COLOR FILTER | FUJIFILM CORPORATION (JP) | 2021-05-13 | — | — | US | disclosed |
| US-10947389-B2 | Composition, film, near infrared cut filter, laminate, pattern forming method, solid image pickup element, image display device, infrared sensor, and color filter | FUJIFILM CORPORATION (JP) | 2021-03-16 | — | — | US | disclosed |
| EP-3660016-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Holdings Corporation (US) | 2020-06-03 | — | — | EP | disclosed |
| CN-107266410-B | Synthesis method of 8-epi-puupehedione | 威海创惠环保科技有限公司 | 2020-01-03 | — | — | CN | disclosed |
| EP-2655374-B1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE HOLDINGS CORP (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-1626720-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. Lundbeck A/S (DK) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004087156-A1 | 4-(2-PHENYLSULFANYL-PHENYL)-PIPERIDINE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS | H. LUNDBECK A/S (DK) | 2004-10-14 | — | — | WO | disclosed |
| EP-0650476-B1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMA CO LTD (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6136826-A | AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0871634-A1 | ARTHROPODICIDAL OXAZOLINES AND THIAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5760058-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| WO-1997013773-A1 | ARTHROPODICIDAL OXAZOLINES AND THIAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-04-17 | — | — | WO | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346753-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, NNMT, NQO1 | TP53 4877/4885CYP3A4 2444/4885NQO1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.