Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5630208 | 0.92 | KDM4E (0.47) | ALDH1A1KDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL5630199 | 0.92 | KDM4E (0.47) | ALDH1A1KDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL5741743 | 0.90 | MEN1 (0.47) | ALDH1A1KDM4EMAPTHRH3MEN1 | |
| SCHEMBL5745896 | 0.85 | HRH3 (0.46) | MAPTHRH3MEN1KMT2A | |
| SCHEMBL5742294 | 0.84 | KMT2A (0.48) | ALDH1A1KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL5629311 | 0.81 | MEN1 (0.50) | ALDH1A1KDM4EMAPTHRH3MEN1 | |
| SCHEMBL5629297 | 0.81 | MEN1 (0.50) | ALDH1A1KDM4EMAPTHRH3MEN1 | |
| SCHEMBL5743962 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL5629617 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL5629612 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4EMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | claimed |