Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741006 | 0.87 | AGPAT2 (0.42) | MCHR1 | |
| SCHEMBL5744121 | 0.85 | MCHR1 (0.51) | MCHR1 | |
| SCHEMBL5742700 | 0.81 | MCHR1 (0.52) | MCHR1MAPTABCG2THRBLMNA | |
| SCHEMBL5744521 | 0.81 | MCHR1 (0.45) | MCHR1MAPTABCG2THRBLMNA | |
| SCHEMBL5742346 | 0.81 | MCHR1 (0.45) | MCHR1MAPTABCG2THRBLMNA | |
| SCHEMBL5740955 | 0.80 | ACP1 (0.51) | MCHR1MAPTABCG2LMNA | |
| SCHEMBL5741862 | 0.79 | AGPAT2 (0.57) | MCHR1MAPTABCG2LMNA | |
| SCHEMBL5741949 | 0.78 | TP53 (0.49) | MCHR1MAPTABCG2 | |
| SCHEMBL5740159 | 0.77 | AGPAT2 (0.47) | MCHR1MAPTABCG2THRBLMNA | |
| SCHEMBL5743466 | 0.75 | AGPAT2 (0.42) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |