Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.51 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743256 | 0.87 | MCHR1 (0.59) | MCHR1AGPAT2 | |
| SCHEMBL5740529 | 0.85 | MCHR1 (0.53) | MCHR1AGPAT2ACP1 | |
| SCHEMBL5744008 | 0.85 | MCHR1 (0.41) | MCHR1 | |
| SCHEMBL5743006 | 0.82 | MCHR1 (0.58) | MCHR1AGPAT2ACP1 | |
| SCHEMBL5741057 | 0.82 | ACP1 (0.57) | MCHR1AGPAT2ACP1 | |
| SCHEMBL5740460 | 0.81 | MCHR1 (0.50) | MCHR1AGPAT2ACP1 | |
| SCHEMBL5742713 | 0.81 | DOT1L (0.56) | MCHR1AGPAT2 | |
| SCHEMBL5742875 | 0.81 | AGPAT2 (0.57) | MCHR1AGPAT2ACP1 | |
| SCHEMBL5741991 | 0.81 | AGPAT2 (0.57) | MCHR1AGPAT2ACP1 | |
| SCHEMBL5743033 | 0.79 | MCHR1 (0.47) | MCHR1AGPAT2ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |