Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215803 | 0.95 | MPO (0.56) | MPOCYSLTR1PIK3CDPKMALDH1A1 | |
| SCHEMBL4770049 | 0.86 | MPO (0.52) | MPOCYSLTR1PIK3CDPKMALDH1A1 | |
| SCHEMBL5217280 | 0.85 | PIK3CD (0.54) | MPOCYSLTR1PIK3CDPKM | |
| SCHEMBL4942765 | 0.85 | PIK3CD (0.54) | MPOCYSLTR1PIK3CDPKMKDM4E | |
| SCHEMBL5246136 | 0.84 | PIK3CD (0.51) | MPOCYSLTR1PIK3CDPKMAPP | |
| SCHEMBL5214629 | 0.84 | PIK3CD (0.51) | MPOCYSLTR1PIK3CDPKMALDH1A1 | |
| SCHEMBL5214659 | 0.83 | PIK3CD (0.57) | MPOCYSLTR1PIK3CDPKMMEN1 | |
| SCHEMBL5215532 | 0.79 | EDNRA (0.44) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL5797414 | 0.78 | PIK3CD (0.47) | MPOCYSLTR1PIK3CDPKMMEN1 | |
| SCHEMBL6020672 | 0.78 | PIK3CD (0.59) | MPOCYSLTR1PIK3CDPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636213-A1 | 3-ARYLOXY AND 3-HETEROARYLOXY SUBSTITUTED BENZO(B) THIOPHENES AS THERAPEUTIC AGENTS WITH PI3K ACTIVITY | Warner-Lambert Company LLC (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108715-A1 | 3-ARYLOXY AND 3-HETEROARYLOXY SUBSTITUTED BENZO(B) THIOPHENES AS THERAPEUTIC AGENTS WITH PI3K ACTIVITY | WARNER-LAMBERT COMPANY LLC (US) | 2004-12-16 | — | — | WO | disclosed |