Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 4/20 | 0.55 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | CTSK | P43235 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5411669 | 1.00 | ATM (0.67) | ATMACEAPPCTSSCTSK | |
| SCHEMBL5411660 | 1.00 | ATM (0.67) | ATMACEAPPCTSSCTSK | |
| SCHEMBL9018576 | 0.92 | MME (0.65) | ATMACEAPPCTSSCTSK | |
| SCHEMBL9018574 | 0.92 | MME (0.65) | ATMACEAPPCTSSCTSK | |
| SCHEMBL9149555 | 0.92 | ATM (0.64) | ATMACEAPPCTSSCTSK | |
| SCHEMBL10654836 | 0.92 | ATM (0.64) | ATMACEAPPCTSSCTSK | |
| SCHEMBL15159951 | 0.92 | ATM (0.73) | ATMACEAPPCTSSCTSK | |
| SCHEMBL23459125 | 0.91 | ATM (0.62) | ATMACEAPPCTSSCTSK | |
| SCHEMBL23459126 | 0.91 | ATM (0.62) | ATMACEAPPCTSSCTSK | |
| SCHEMBL23168374 | 0.91 | ATM (0.65) | ATMACEAPPCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250017890-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-01-16 | — | — | US | disclosed |
| CN-111094238-B | Carbamoyl phenylalaninol analogues and uses thereof | 杰资制药爱尔兰有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-20220401401-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | HERCULES CAPITAL, INC. | 2022-12-22 | — | — | US | disclosed |
| US-20220401401-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | HERCULES CAPITAL, INC. | 2022-12-22 | — | — | US | disclosed |
| US-11413264-B2 | Carbamoyl phenylalaninol analogs and uses thereof | JAZZ PHARMACEUTICALS IRELAND LIMITED (IE) | 2022-08-16 | — | — | US | disclosed |
| US-20210093603-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2021-04-01 | — | — | US | disclosed |
| US-20210093603-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2021-04-01 | — | — | US | disclosed |
| CN-111094238-A | Carbamoyl phenylalaninol analogs and uses thereof | 杰资制药爱尔兰有限公司 | 2020-05-01 | — | — | CN | disclosed |
| US-20060223814-A1 | Nk-2 antagonist basic linear compounds and formulations containing them | MENARINI RICERCHE S.P.A. (IT) | 2006-10-05 | — | — | US | disclosed |
| EP-1620432-A1 | NK-2 ANTAGONIST BASIC LINEAR COMPOUNDS AND FORMULATIONS CONTAINING THEM | Menarini Ricerche S.p.A. (IT) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004094412-A1 | NK-2 ANTAGONIST BASIC LINEAR COMPOUNDS AND FORMULATIONS CONTAINING THEM | MENARINI RICERCHE S.P.A. (IT) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093603-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | DNPEP, CPS1, GLS | ATM 4027/4885ACE 16/4885APP 2700/4885 |
| US-11413264-B2 | Carbamoyl phenylalaninol analogs and uses thereof | DNPEP, CPS1, GLS | ATM 4027/4885ACE 16/4885APP 2700/4885 |
| US-20220401401-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | DNPEP, CPS1, GLS | ATM 4027/4885ACE 16/4885APP 2700/4885 |
| US-20250017890-A1 | CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF | DNPEP, CPS1, GLS | ATM 4027/4885ACE 16/4885APP 2700/4885 |
| US-20060223814-A1 | Nk-2 antagonist basic linear compounds and formulations containing them | BDKRB2, KLK2, BDKRB1 | ATM 2561/4885ACE 708/4885APP 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.