Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745667 | 0.91 | BRD4 (0.34) | BRD4SCN8A | |
| SCHEMBL5745800 | 0.87 | DGAT1 (0.32) | — | |
| SCHEMBL5744915 | 0.86 | DGAT1 (0.32) | — | |
| SCHEMBL5746720 | 0.86 | BRD4 (0.33) | BRD4 | |
| SCHEMBL5744596 | 0.85 | ALOX5 (0.30) | — | |
| SCHEMBL5743217 | 0.84 | BRD4 (0.33) | BRD4SCN8A | |
| SCHEMBL5744102 | 0.84 | — | — | |
| SCHEMBL4499563 | 0.81 | BCDIN3D (0.31) | SCN8A | |
| SCHEMBL4497082 | 0.80 | CALCRL (0.32) | SCN8A | |
| SCHEMBL5746562 | 0.78 | DGAT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689738-A2 | HETEROCYCLIC ANTI-MIGRAINE AGENTS | Bristol-Myers Squibb Company (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005056550-A2 | HETEROCYCLIC ANTI-MIGRAINE AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-23 | — | — | WO | disclosed |