Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080762 | 0.76 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL3843472 | 0.75 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3841747 | 0.73 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL2507429 | 0.71 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL9981362 | 0.71 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL3838950 | 0.71 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3839529 | 0.70 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL2506464 | 0.70 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL9982401 | 0.70 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL2507433 | 0.70 | KCNH2 (0.48) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578743-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-29 | — | — | EP | disclosed |
| EP-1578743-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058144-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-07-15 | — | — | WO | disclosed |