SCHEMBL5745131

SCHEMBL5745131

CO/C=C(/C(=O)OC)c1ccccc1COc1csc(C(F)(F)F)n1

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.36
OPRL1 P41146 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5626855 0.91 OPRL1 (0.32) HIF1AOPRL1MRGPRX4
SCHEMBL5626865 0.91 OPRL1 (0.32) HIF1AOPRL1MRGPRX4
Picoxystrobin SCHEMBL29377786 0.82 HIF1A (0.39) HIF1AMRGPRX4
Picoxystrobin SCHEMBL675260 0.82 HIF1A (0.39) HIF1AMRGPRX4
Picoxystrobin SCHEMBL18977 0.82 HIF1A (0.39) HIF1AMRGPRX4
SCHEMBL5742217 0.81 HIF1A (0.36) HIF1AOPRL1
Picoxystrobin SCHEMBL17701174 0.81 HIF1A (0.39) HIF1AMRGPRX4
SCHEMBL28336660 0.81 HIF1A (0.38) HIF1A
SCHEMBL5743541 0.80 PDE10A (0.39)
SCHEMBL5745294 0.80 HIF1A (0.35) HIF1AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453817-B1 THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY ISAGRO RICERCA SRL (IT) 2006-04-26 EP claimed