Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5628053 | 0.91 | MRGPRX4 (0.33) | HIF1AL3MBTL1MRGPRX4 | |
| SCHEMBL5628065 | 0.91 | MRGPRX4 (0.33) | HIF1AL3MBTL1MRGPRX4 | |
| SCHEMBL5742217 | 0.89 | HIF1A (0.36) | HIF1ACSNK1DPLA2G1BATG4BHPGD | |
| SCHEMBL5628832 | 0.80 | MRGPRX4 (0.33) | HIF1AMRGPRX4 | |
| SCHEMBL5628822 | 0.80 | MRGPRX4 (0.33) | HIF1AMRGPRX4 | |
| SCHEMBL5745131 | 0.80 | HIF1A (0.36) | HIF1AMRGPRX4 | |
| SCHEMBL5628845 | 0.79 | HTT (0.34) | HIF1AMRGPRX4 | |
| SCHEMBL5628853 | 0.79 | HTT (0.34) | HIF1AMRGPRX4 | |
| SCHEMBL30368058 | 0.78 | HIF1A (0.38) | HIF1ALMNA | |
| SCHEMBL18292000 | 0.78 | HIF1A (0.38) | HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | claimed |