Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5626841 | 0.91 | PDE10A (0.39) | PDE10AKDM4EALDH1A1APOBEC3GCPT1A | |
| SCHEMBL5626849 | 0.91 | PDE10A (0.39) | PDE10AKDM4EALDH1A1APOBEC3GCPT1A | |
| SCHEMBL7171946 | 0.82 | MAPK1 (0.41) | KDM4EALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL7171950 | 0.82 | MAPK1 (0.41) | KDM4EALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL5742294 | 0.82 | KMT2A (0.48) | KDM4EALDH1A1APOBEC3GHSD17B10HPGD | |
| SCHEMBL5745131 | 0.80 | HIF1A (0.36) | — | |
| SCHEMBL5743543 | 0.80 | PDE10A (0.39) | PDE10AKDM4EALDH1A1APOBEC3GKLKB1 | |
| SCHEMBL5744005 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1APOBEC3GHSD17B10HPGD | |
| SCHEMBL9256030 | 0.75 | GABRA5 (0.39) | KDM4E | |
| SCHEMBL12671601 | 0.75 | GABRA5 (0.39) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453817-B1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2006-04-26 | — | — | EP | claimed |