Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745369 | 0.89 | PTGDR2 (0.50) | PTGDR2TP53 | |
| SCHEMBL5743757 | 0.88 | ANPEP (0.47) | LMNAPOLBPTGDR2TP53MAPT | |
| SCHEMBL6847480 | 0.77 | PPARG (0.54) | LMNACASP3TP53 | |
| SCHEMBL10648774 | 0.64 | PPARG (0.47) | LMNAPOLBALDH1A1MAPT | |
| SCHEMBL10512057 | 0.63 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL523176 | 0.63 | CASP3 (0.55) | LMNAPOLBALDH1A1CASP3MAPT | |
| SCHEMBL4969017 | 0.62 | NPSR1 (0.76) | LMNAPOLBALDH1A1MAPT | |
| SCHEMBL10650186 | 0.62 | NPSR1 (0.70) | LMNAPOLBALDH1A1MAPTPKM | |
| SCHEMBL4969646 | 0.62 | POLB (0.61) | LMNAPOLBALDH1A1OPRL1 | |
| SCHEMBL16315850 | 0.62 | TP53 (0.54) | LMNAALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |
| EP-1173427-A1 | HYDROXAMIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063197-A1 | HYDROXAMIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-10-26 | — | — | WO | disclosed |