Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746254 | 0.88 | PPARG (0.45) | MCL1GAAPPARGKMT2AALDH1A1 | |
| SCHEMBL5747286 | 0.85 | GAA (0.47) | MCL1GAAPPARGKMT2AALDH1A1 | |
| SCHEMBL5796548 | 0.83 | MCL1 (0.53) | MCL1GAAPPARGALDH1A1THRB | |
| Hydroxyamine SCHEMBL5793019 | 0.82 | MCL1 (0.51) | MCL1GAAPPARGALDH1A1THRB | |
| Hydroxyamine SCHEMBL5797278 | 0.82 | MCL1 (0.46) | MCL1GAAPPARGHSD17B3GSK3B | |
| Hydroxyamine SCHEMBL5794204 | 0.82 | MCL1 (0.46) | MCL1GAAPPARGKMT2AALDH1A1 | |
| SCHEMBL5744163 | 0.80 | MCL1 (0.52) | MCL1GAAPPARGKMT2AALDH1A1 | |
| SCHEMBL5745464 | 0.80 | GAA (0.41) | MCL1GAAPPARGKMT2AALDH1A1 | |
| SCHEMBL5745463 | 0.80 | GAA (0.53) | MCL1GAAPPARGALDH1A1THRB | |
| SCHEMBL5747345 | 0.79 | PPARG (0.54) | MCL1GAAPPARGKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |