Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL5793019 | 0.98 | MCL1 (0.51) | MCL1GSK3BLMNAHTTPDPK1 | |
| SCHEMBL4972058 | 0.89 | GSK3B (0.49) | MCL1GSK3BLMNAHTTGAA | |
| SCHEMBL5793022 | 0.88 | PPARG (0.48) | GSK3BLMNAHTTGAASMN1; SMN2 | |
| SCHEMBL5746821 | 0.88 | LMNA (0.53) | LMNAHTTSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL5797144 | 0.86 | GSK3B (0.47) | GSK3BLMNAHTTSMN1; SMN2PPARG | |
| SCHEMBL5744163 | 0.85 | MCL1 (0.52) | MCL1GSK3BPDPK1GAASMN1; SMN2 | |
| SCHEMBL21783138 | 0.83 | MCL1 (0.67) | MCL1GAAPPARGTSHRL3MBTL1 | |
| SCHEMBL5798276 | 0.83 | MCL1 (0.50) | MCL1GSK3BPDPK1GAASMN1; SMN2 | |
| SCHEMBL5745194 | 0.83 | MCL1 (0.50) | MCL1GSK3BHTTPDPK1GAA | |
| SCHEMBL9035893 | 0.82 | GSK3B (0.59) | GSK3BLMNAHTTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |