Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745194 | 0.88 | MCL1 (0.50) | PPARGGAAMCL1ALDH1A1THRB | |
| SCHEMBL5794846 | 0.85 | PPARG (0.45) | PPARGGAAMCL1ALDH1A1KMT2A | |
| SCHEMBL5797144 | 0.85 | GSK3B (0.47) | PPARGCCKBRTHRBSRC | |
| SCHEMBL5745384 | 0.82 | PPARG (0.49) | PPARGGAAMCL1ALDH1A1KMT2A | |
| SCHEMBL5745589 | 0.81 | MCL1 (0.47) | PPARGGAAMCL1SRC | |
| SCHEMBL5747286 | 0.81 | GAA (0.47) | PPARGGAAMCL1ALDH1A1THRB | |
| Hydroxyamine SCHEMBL5797278 | 0.80 | MCL1 (0.46) | PPARGGAAMCL1SRC | |
| SCHEMBL5747345 | 0.79 | PPARG (0.54) | PPARGGAAMCL1ALDH1A1KMT2A | |
| SCHEMBL5745670 | 0.77 | PPARG (0.52) | PPARGGAAMCL1KMT2A | |
| SCHEMBL5746078 | 0.77 | PPARG (0.53) | PPARGGAAMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |