Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794846 | 0.93 | PPARG (0.45) | PPARGGAAMCL1DRD2KMT2A | |
| SCHEMBL5745589 | 0.90 | MCL1 (0.47) | PPARGGAAMCL1DRD2SMN1; SMN2 | |
| SCHEMBL5747164 | 0.89 | PPARG (0.52) | PPARGGAAMCL1DRD2KMT2A | |
| Hydroxyamine SCHEMBL5797278 | 0.88 | MCL1 (0.46) | PPARGGAAMCL1DRD2SMN1; SMN2 | |
| SCHEMBL5743605 | 0.86 | PPARG (0.49) | PPARGMCL1DRD2SMN1; SMN2LMNA | |
| SCHEMBL6847175 | 0.85 | PPARG (0.54) | PPARGGAAMCL1MAPTSMN1; SMN2 | |
| SCHEMBL5746105 | 0.85 | PPARG (0.49) | PPARGGAAMCL1DRD2MAPT | |
| SCHEMBL5746051 | 0.84 | MCL1 (0.45) | PPARGMCL1KMT2AMEN1PABPC1 | |
| SCHEMBL1238384 | 0.84 | PABPC1 (0.39) | PPARGDRD2KMT2AMEN1PABPC1 | |
| SCHEMBL1239775 | 0.84 | PABPC1 (0.39) | PPARGDRD2KMT2AMEN1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |