Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 5/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL5797278 | 0.98 | MCL1 (0.46) | MCL1GAAPPARGDRD2SRC | |
| SCHEMBL5745384 | 0.90 | PPARG (0.49) | MCL1GAAPPARGDRD2SMN1; SMN2 | |
| SCHEMBL5794846 | 0.86 | PPARG (0.45) | MCL1GAAPPARGDRD2 | |
| SCHEMBL5745592 | 0.84 | GAA (0.39) | MCL1GAAPPARGDRD2HSD17B3 | |
| SCHEMBL5745194 | 0.83 | MCL1 (0.50) | MCL1GAAPPARGHSD17B3HTT | |
| SCHEMBL5744163 | 0.83 | MCL1 (0.52) | MCL1GAAPPARGHSD17B3SMN1; SMN2 | |
| SCHEMBL5798276 | 0.81 | MCL1 (0.50) | MCL1GAAPPARGHSD17B3SMN1; SMN2 | |
| SCHEMBL5746078 | 0.81 | PPARG (0.53) | MCL1GAAPPARGDRD2HSD17B3 | |
| SCHEMBL5746254 | 0.81 | PPARG (0.45) | MCL1GAAPPARGSRC | |
| SCHEMBL5796548 | 0.80 | MCL1 (0.53) | MCL1GAAPPARGSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |