Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5745517

Cc1ccc(S(=O)(=O)O)c(C)c1.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEP1B Q16820 1/20 0.47
▸ RAPGEF4 Q8WZA2 1/20 0.46
▸ ALDH1A1 P00352 5/20 0.46
▸ HPGD P15428 2/20 0.46
▸ MAPT P10636 2/20 0.46
▸ POLB P06746 1/20 0.46
▸ ALOX12 P18054 1/20 0.46
▸ GFER P55789 1/20 0.46
▸ KMT2A Q03164 2/20 0.45
▸ HSD17B10 Q99714 1/20 0.44
▸ LMNA P02545 4/20 0.44
▸ SMN1; SMN2 Q16637 4/20 0.44
▸ GAA P10253 2/20 0.44
▸ TP53 P04637 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ MAP1LC3B Q9GZQ8 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ F2 P00734 1/20 0.42
▸ PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29702850 1.00 MEP1B (0.47) MEP1BRAPGEF4ALDH1A1HPGDMAPT
SCHEMBL29454656 0.98 MEP1B (0.49) MEP1BRAPGEF4ALDH1A1HPGDMAPT
SCHEMBL26645 0.98 MEP1B (0.49) MEP1BRAPGEF4ALDH1A1HPGDMAPT
SCHEMBL3105642 0.96 MEP1B (0.47) MEP1BRAPGEF4ALDH1A1HPGDMAPT
SCHEMBL6918128 0.96 MEP1B (0.47) MEP1BRAPGEF4ALDH1A1HPGDMAPT
Water SCHEMBL2695854 0.96 MEP1B (0.47) MEP1BRAPGEF4ALDH1A1HPGDMAPT
SCHEMBL6915075 0.96 MEP1B (0.47) MEP1BRAPGEF4ALDH1A1HPGDMAPT
Water SCHEMBL21412761 0.96 MEP1B (0.47) MEP1BRAPGEF4ALDH1A1HPGDMAPT
SCHEMBL6909827 0.96 MEP1B (0.47) MEP1BRAPGEF4ALDH1A1HPGDMAPT
SCHEMBL6908120 0.96 MEP1B (0.47) MEP1BRAPGEF4ALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250268840-A1 USE OF NANO-CARRIERS FOR DELIVERY OF ACTIVE AGENTS LANDA LABS (2012) LTD. (IL) 2025-08-28 — — US disclosed
US-20240082118-A1 TOPICAL COMPOSITIONS AND METHODS OF PREPARING THE SAME LANDA LABS (2012) LTD. (IL) 2024-03-14 — — US disclosed
WO-2023091342-A1 PRESERVATION SYSTEM FOR STABILIZING SPORE-FORMING MICROBIALS PHIBRO ANIMAL HEALTH CORPORATION (US) 2023-05-25 — — WO disclosed
US-20230151324-A1 PRESERVATION SYSTEM FOR STABILIZING SPORE-FORMING MICROBIALS PHIBRO ANIMAL HEALTH CORPORATION (US) 2023-05-18 — — US disclosed
EP-1288213-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL|ACETIC ACID DERIVATIVES KANEKA CORP (JP) 2006-11-29 — — EP disclosed
US-20060246557-A1 Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives KANEKA CORPORATION (JP) 2006-11-02 — — US disclosed
US-7094594-B2 Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives KANEKA CORPORATION (JP) 2006-08-22 — — US disclosed
US-20050080277-A1 Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives KANEKA CORPORATION (JP) 2005-04-14 — — US disclosed
EP-1288213-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2- 6-(HYDROXY-METHYL)-1,3-DIOXAN-4-YL]ACETIC ACID DERIVATIVES KANEKA CORPORATION (JP) 2003-03-05 — — EP disclosed
US-6101946-A Microarray printing device including printing pins with flat tips and exterior channel and method of manufacture TELECHEM INTERNATIONAL INC. (US) 2000-08-15 — — US disclosed
US-4687593-A MIXTURE OF 2-PHENYL ALKYL BENZENE SULFONATE AND ALKYLATED DIPHENYL ETHER SULFATE MONSANTO COMPANY (US) 1987-08-18 — — US disclosed
US-4645623-A WATER SOLUBLE MIXTURE OF 2-PHENYL ALKYLBENZENE SULFONATES AND ALKYLATED DIPHENYL OXIDE SULFONATES MONSANTO COMPANY (US) 1987-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246557-A1 Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives HAAO, APEH, HPD MEP1B 1690/4885RAPGEF4 2467/4885ALDH1A1 174/4885
US-20050080277-A1 Process for preparing optically active 2-[6-(hydroxy-methyl)-1,3-dioxan-4-yl] acetic acid derivatives HAAO, APEH, HPD MEP1B 2191/4885RAPGEF4 2425/4885ALDH1A1 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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