Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749349 | 0.86 | KDM4E (0.51) | KDM4EALDH1A1GAAPARP1PDPK1 | |
| SCHEMBL5665216 | 0.84 | NR4A1 (0.60) | KDM4EALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL5749898 | 0.82 | KDM4E (0.71) | KDM4EALDH1A1GAAPARP1PDPK1 | |
| SCHEMBL5751282 | 0.82 | KDM4E (0.71) | KDM4EALDH1A1GAAPARP1PDPK1 | |
| SCHEMBL8912256 | 0.79 | HDAC8 (0.64) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| Water SCHEMBL3981101 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1GAAPARP1PDPK1 | |
| SCHEMBL5191012 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1GAAPOLBSMN1; SMN2 | |
| SCHEMBL43084 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1GAAPARP1PDPK1 | |
| SCHEMBL29381201 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1GAAPARP1PDPK1 | |
| SCHEMBL18859029 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1GAAPARP1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |