Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.64 |
| ▸ | MMP3 | P08254 | 1/20 | 0.64 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5665216 | 0.81 | NR4A1 (0.60) | HDAC8MMP3KDM4ENR4A1NR4A2 | |
| SCHEMBL5745519 | 0.79 | KDM4E (0.51) | HDAC8MMP3PLK1GAASMN1; SMN2 | |
| SCHEMBL2230679 | 0.78 | HDAC8 (1.00) | HDAC8MMP3PLAUPLK1HDAC1 | |
| SCHEMBL29816659 | 0.78 | HDAC8 (1.00) | HDAC8MMP3PLAUPLK1HDAC1 | |
| SCHEMBL7872561 | 0.78 | HDAC8 (1.00) | HDAC8MMP3PLAUPLK1HDAC1 | |
| Sulfuric Acid SCHEMBL28957208 | 0.72 | HDAC8 (0.86) | HDAC8MMP3PLAUPLK1HDAC1 | |
| SCHEMBL292681 | 0.71 | ALDH1A1 (0.44) | KDM4EHIF1ALMNAPOLBALDH1A1 | |
| SCHEMBL6633516 | 0.70 | NR4A1 (0.60) | HDAC8MMP3SMN1; SMN2KDM4ELMNA | |
| SCHEMBL28629544 | 0.70 | HDAC8 (0.64) | HDAC8MMP3PLAUPLK1HDAC1 | |
| SCHEMBL384025 | 0.70 | CYP1A2 (0.56) | PLAUKDM4ELMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |