Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 5/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.36 |
| ▸ | MET | P08581 | 4/20 | 0.36 |
| ▸ | TEK | Q02763 | 4/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749898 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| SCHEMBL29498815 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| SCHEMBL634215 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| SCHEMBL29100415 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| SCHEMBL30181949 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| SCHEMBL5749349 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| SCHEMBL5745519 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| SCHEMBL25192670 | 0.82 | KDM4E (0.96) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| SCHEMBL497724 | 0.82 | KDM4E (0.96) | KDM4EALDH1A1GAAPDPK1PARP1 | |
| Hydrochloric Acid SCHEMBL4811305 | 0.80 | KDM4E (0.93) | KDM4EALDH1A1GAAPDPK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |