Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748489 | 0.85 | CYP1A2 (0.42) | CYP1A2CYP2A6ELANENPC1RAB9A | |
| SCHEMBL5746960 | 0.80 | TLR8 (0.48) | ALDH1A1KDM4ETP53HSD17B10LMNA | |
| SCHEMBL5747288 | 0.80 | TLR8 (0.48) | ALDH1A1KDM4ETP53HSD17B10LMNA | |
| SCHEMBL411739 | 0.75 | CYP1A2 (0.57) | CYP1A2CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12044582 | 0.75 | CYP1A2 (0.57) | CYP1A2CYP2A6NPC1RAB9AKDM4E | |
| SCHEMBL14439066 | 0.71 | CYP1A2 (0.52) | CYP1A2CYP2A6ELANENPC1RAB9A | |
| SCHEMBL209493 | 0.71 | KDM4E (0.38) | CYP1A2CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3384257 | 0.71 | ALDH1A1 (0.47) | CYP1A2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL207987 | 0.71 | NR4A2 (0.47) | CYP1A2CYP2A6SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL208857 | 0.71 | BACE1 (0.48) | CYP1A2CYP2A6NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |
| US-4380633-A | Methine dyes from tetrahydroquinoline compounds containing N-thioether substituents | EASTMAN KODAK COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| US-4260742-A | Methine dyes from tetrahydroquinoline compounds containing n-thioether substituents | EASTMAN KODAK COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4161601-A | YELLOW POLYESTERS | EASTMAN KODAK COMPANY (US) | 1979-07-17 | — | — | US | disclosed |