Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745559 | 0.85 | CYP1A2 (0.42) | CYP1A2CYP2A6SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5746267 | 0.80 | TLR8 (0.48) | ALDH1A1LMNAKDM4ETP53HSD17B10 | |
| SCHEMBL28140543 | 0.77 | — | — | |
| SCHEMBL7590065 | 0.77 | XDH (0.41) | CYP1A2SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL28140639 | 0.77 | — | — | |
| SCHEMBL407633 | 0.75 | CYP1A2 (0.55) | CYP1A2CYP2A6RAB9AALDH1A1KMT2A | |
| SCHEMBL10935659 | 0.74 | KMT2A (0.45) | CYP1A2SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10234988 | 0.73 | CYP1A2 (0.59) | CYP1A2CYP2A6SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7630593 | 0.71 | KDM4E (0.52) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL206393 | 0.71 | BACE1 (0.47) | CYP1A2CYP2A6NPC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |