Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 11/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746344 | 0.90 | MME (0.41) | NR3C2JAK2TYK2MAPKAPK2 | |
| SCHEMBL5750072 | 0.88 | KDM4E (0.42) | — | |
| SCHEMBL5746333 | 0.88 | KDM4E (0.42) | — | |
| SCHEMBL5745314 | 0.88 | KDM4E (0.42) | — | |
| SCHEMBL5748820 | 0.86 | NOS2 (0.52) | NR3C2JAK2TYK2MAPKAPK2MAPK10 | |
| SCHEMBL5748107 | 0.82 | NR3C2 (0.46) | NR3C2JAK2TYK2MAPKAPK2MAPK10 | |
| SCHEMBL10238962 | 0.77 | NR3C2 (0.44) | NR3C2NOS3NOS1NOS2 | |
| SCHEMBL14367992 | 0.77 | GRIN2D (0.44) | — | |
| SCHEMBL5770617 | 0.76 | RIOK2 (0.38) | NR3C2MAPK10KARS1 | |
| SCHEMBL5750225 | 0.75 | RIOK2 (0.38) | NR3C2MAPK10GRM5KARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |