Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750072 | 1.00 | KDM4E (0.42) | KDM4ETDP1L3MBTL1LPLLIPG | |
| SCHEMBL5746333 | 1.00 | KDM4E (0.42) | KDM4ETDP1L3MBTL1LPLLIPG | |
| SCHEMBL5746344 | 0.94 | MME (0.41) | KDM4ETDP1L3MBTL1HPGDMME | |
| SCHEMBL5745899 | 0.88 | NR3C2 (0.40) | — | |
| SCHEMBL5748565 | 0.87 | ALOX12 (0.45) | KDM4ETDP1L3MBTL1LPLLIPG | |
| SCHEMBL5749197 | 0.84 | KCNH3 (0.44) | KDM4ETDP1L3MBTL1PPARGPPARA | |
| SCHEMBL5750951 | 0.84 | KCNH3 (0.44) | KDM4ETDP1L3MBTL1PPARGPPARA | |
| SCHEMBL5748767 | 0.84 | KCNH3 (0.44) | KDM4ETDP1L3MBTL1PPARGPPARA | |
| SCHEMBL5748770 | 0.81 | LMNA (0.42) | KDM4ETDP1L3MBTL1HPGD | |
| SCHEMBL5748820 | 0.81 | NOS2 (0.52) | KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |