Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.84 |
| ▸ | MAT2A | P31153 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4857420 | 0.99 | TSPO (0.82) | TSPOMAT2AMAPT | |
| SCHEMBL197375 | 0.91 | TSPO (1.00) | TSPOMAT2AMAPT | |
| SCHEMBL10042107 | 0.90 | TSPO (0.84) | TSPOMAPT | |
| SCHEMBL4842381 | 0.90 | TSPO (0.83) | TSPOMAT2A | |
| SCHEMBL17959426 | 0.90 | TSPO (0.82) | TSPOMAT2A | |
| Hydrochloric Acid SCHEMBL4845791 | 0.89 | TSPO (0.82) | TSPOMAT2A | |
| SCHEMBL5746627 | 0.89 | TSPO (0.66) | TSPO | |
| Hydrochloric Acid SCHEMBL4843306 | 0.88 | TSPO (0.65) | TSPO | |
| SCHEMBL17959423 | 0.86 | TSPO (0.83) | TSPOMAT2A | |
| SCHEMBL4846011 | 0.86 | TSPO (0.77) | TSPOMAT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492792-B1 | 3-HETEROARYL-3,5-DIHYDRO-4-OXO-4H-PYRIDAZINO¬4,5-B|INDOLE-1-ACETAMIDE DERIVATIVES, PREPARATION AND USE THEREOF IN MEDICAMENTS | SANOFI AVENTIS (FR) | 2006-03-29 | — | — | EP | disclosed |