SCHEMBL197375

SCHEMBL197375

CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccc(Cl)cc1n2C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 1.00
MAT2A P31153 3/20 0.51
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10042107 0.91 TSPO (0.84) TSPOMAPT
SCHEMBL5745978 0.91 TSPO (0.84) TSPOMAT2AMAPT
SCHEMBL17959423 0.91 TSPO (0.83) TSPOMAT2A
SCHEMBL4842381 0.91 TSPO (0.83) TSPOMAT2A
SCHEMBL8959261 0.91 TSPO (0.83) TSPOMAT2AMAPT
Hydrochloric Acid SCHEMBL4857420 0.90 TSPO (0.82) TSPOMAT2AMAPT
SCHEMBL17959426 0.90 TSPO (0.82) TSPOMAT2A
SCHEMBL7496839 0.90 TSPO (0.82) TSPOMAT2AMAPT
Hydrochloric Acid SCHEMBL4845791 0.90 TSPO (0.82) TSPOMAT2A
SCHEMBL5702540 0.90 TSPO (0.81) TSPOMAT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
US-20250019701-A1 TREATMENT FOR INFLAMMATORY DISEASE THE ROYAL VETERINARY COLLEGE (GB) 2025-01-16 US claimed
EP-4429700-A1 TREATMENT FOR INFLAMMATORY DISEASE The Royal Veterinary College (GB) 2024-09-18 EP claimed
WO-2023212244-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS, INC. (US) 2023-11-02 WO claimed
WO-2023084198-A1 TREATMENT FOR INFLAMMATORY DISEASE THE ROYAL VETERINARY COLLEGE (GB) 2023-05-19 WO claimed
US-20170160287-A1 USE OF 7-CHLORO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-B] INDOLE-1-ACETAMIDE AS A BIOMARKER OF PERIPHERAL BENZODIAZEPINE RECEPTOR LEVELS SANOFI (FR) 2017-06-08 US claimed
EP-1791524-B1 PHARMACEUTICAL COMPOSITION COMPRISING A SOLID DISPERSION WITH A POLYMER MATRIX CONTAINING A CONTINUOUS POLYDEXTROSE PHASE AND A CONTINUOUS PHASE OF A POLYMER OTHER THAN POLYDEXTROSE SANOFI SA (FR) 2014-11-19 EP claimed
US-20140212493-A1 Highly Bioavailable Composition Containing Eprosartan - Poloxamer Complex or 2-(7-Chloro-5-Methyl-4-Oxo-3-Phenyl-4,5-Dihydro-3H-Pyridazine (4,5-b)Indol-1-yl)-N,N-Dimethylacetamide - Poloxamer Complex BVM HOLDING CO. (US) 2014-07-31 US claimed
EP-2349352-B1 Use of 7-chloro-N,N,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide as a biomarker of peripheral benzodiazepine receptor levels SANOFI SA (FR) 2013-12-25 EP claimed
EP-1926476-B1 AMORPHOUS SOLID DISPERSIONS OF 7-CHLORO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-3,5,-DIHYDRO-4H-PYRIDAZINO[4,5-B]INDOLE-1-ACETAMIDE SANOFI AVENTIS US LLC (US) 2013-04-10 EP claimed
WO-2010021905-A1 PROCESS FOR PREPARING POLYMORPH OF 7-CHLORO-N, N,5-TRIMETHYL-4-OXO-3-PHENYL-3,5-DIHYDR0-4H-PYRIDAZIN0[4,5-B]INDOLE-1-ACETAMIDE SANOFI-AVENTIS U.S. LLC (US) 2010-02-25 WO claimed
US-20080160080-A1 AMORPHOUS SOLID DISPERSIONS SANOFI-AVENTIS U.S. LLC (US) 2008-07-03 US claimed
US-20080139569-A1 NOVEL CRYSTALLINE FORM SANOFI-AVENTIS U.S. LLC. (US) 2008-06-12 US claimed
US-20080038359-A1 Stable Nanoparticle Formulations SANOFI-AVENTIS U.S. LLC (US) 2008-02-14 US claimed
EP-1878443-A1 THERAPEUTIC AGENT FOR NEUROPATHIC PAIN Japan Science and Technology Agency (JP) 2008-01-16 EP claimed
US-20070243257-A1 PHARMACEUTICAL COMPOSITION COMPRISING A SOLID DISPERSION WITH A POLYMER MATRIX CONTAINING A CONTINUOUS POLYDEXTROSE PHASE AND A CONTINUOUS PHASE OF A POLYMER OTHER THAN POLYDEXTROSE SANOFI-AVENTIS (FR) 2007-10-18 US claimed
EP-1148881-B1 USE OF PYRIDAZINO ¬4,5-(b)|-INDOLE-1-ACETAMIDE DERIVATIVES FOR PREPARING MEDICINES FOR TREATING DISEASES RELATED TO THE DYSFUNCTION OF PERIPHERAL BENZODIAZEPIN RECEPTORS SANOFI AVENTIS (FR) 2006-08-09 EP claimed
US-20050220881-A1 Pharmaceutical composition BVM HOLDING CO. 2005-10-06 US claimed
WO-2005034999-A2 COMPOSITION COMPRISING ASSOCIATION COMPLEX OF A PHARMACEUTICAL AND A POLOXAMER BVM HOLDING CO. (US) 2005-04-21 WO claimed
US-6395729-B1 CENTRAL NERVOUS SYSTEM DISORDERS SANOFI-SYNTHELABO (FR) 2002-05-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080160080-A1 AMORPHOUS SOLID DISPERSIONS HTR3D, ATXN2, SLC18A1 TSPO 1939/4885MAT2A 1051/4885MAPT 239/4885
US-20080038359-A1 Stable Nanoparticle Formulations NPC1L1, NPC1, CD63 TSPO 173/4885MAT2A 2736/4885MAPT 70/4885
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS HTR2A, HTR5A, HTR6 TSPO 1014/4885MAT2A 350/4885MAPT 1647/4885
US-20080139569-A1 NOVEL CRYSTALLINE FORM IDO1, CYP3A5, ACIN1 TSPO 4657/4885MAT2A 332/4885MAPT 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.