SCHEMBL5746192

SCHEMBL5746192

O=Cc1cc2ccc3c[c]cc4ccc(c1)c2c34

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 8/20 0.34
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 1/20 0.31
PTGS2 P35354 1/20 0.31
RAB9A P51151 1/20 0.31
AMY1A P0DUB6 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ALDH5A1 P51649 1/20 0.30
ABAT P80404 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9797581 0.86 CYP2A6 (0.41) CYP2A6ALDH1A1KDM4EPTGS2RAB9A
SCHEMBL29590945 0.77 ALDH1A1 (0.52) CYP2A6ALDH1A1KDM4ERAB9AAMY1A
SCHEMBL3735918 0.77 ALDH1A1 (0.52) CYP2A6ALDH1A1KDM4ERAB9AAMY1A
SCHEMBL5748718 0.76 CYP2A6 (0.35) CYP2A6ALDH1A1KDM4EPTGS2RAB9A
SCHEMBL510450 0.75 ALDH1A1 (0.41) ALDH1A1HSD17B10
SCHEMBL5747127 0.71 CYP1A2 (0.40) CYP2A6ALDH1A1KDM4EAMY1AHSD17B10
SCHEMBL5749324 0.71 CYP2A6 (0.33) CYP2A6AMY1A
SCHEMBL14140030 0.71 MEN1 (0.62) ALDH1A1KDM4EHSD17B10
SCHEMBL5750311 0.71 CYP2A6 (0.40) CYP2A6ALDH1A1KDM4EPTGS2RAB9A
SCHEMBL28322355 0.71 CYP2A6 (0.34) CYP2A6ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060293503-A1 Polyaminopyridines and method for producing same SUMITOMO SEIKA CHEMICALS CO., LTD (JP) 2006-12-28 US disclosed
EP-1669390-A1 POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-06-14 EP disclosed