Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 5/20 | 0.66 |
| ▸ | RPS27 | P42677 | 4/20 | 0.53 |
| ▸ | PIM1 | P11309 | 5/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.42 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3546792 | 0.81 | SQOR (0.55) | SQORCNR1ADORA1MEN1KMT2A | |
| SCHEMBL22208394 | 0.80 | SQOR (1.00) | SQORPIM1CNR1ADORA1MEN1 | |
| SCHEMBL3544165 | 0.71 | ADORA1 (0.47) | SQORCLK4ADORA1MEN1KMT2A | |
| SCHEMBL4072641 | 0.70 | SQOR (0.56) | SQORRPS27PIM1CNR1MAPK8 | |
| SCHEMBL11483017 | 0.69 | ABCB1 (0.49) | SQORCLK4ADORA1MEN1KMT2A | |
| SCHEMBL22208360 | 0.68 | SQOR (0.72) | SQORPIM1ADORA1KMT2AL3MBTL1 | |
| SCHEMBL17330432 | 0.68 | SQOR (0.56) | SQORL3MBTL1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6446566 | 0.68 | ADORA1 (0.63) | SQORADORA1 | |
| SCHEMBL5388756 | 0.67 | POLB (0.67) | SQORL3MBTL1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13514356 | 0.67 | RPS27 (0.86) | RPS27MAPK8MAPK9MAP4K4MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368320-B1 | SUBSTITUTED 2-OXY-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-08-16 | — | — | EP | claimed |