Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750449 | 0.73 | PARP1 (0.56) | PARP1KDM4EL3MBTL1PLK4MAP4K4 | |
| SCHEMBL4292765 | 0.72 | PARP1 (0.46) | PARP1KDM4ECSNK1A1DYRK1BALDH1A1 | |
| SCHEMBL2606619 | 0.72 | PARP1 (0.62) | PARP1KDM4EL3MBTL1ALDH1A1HSD17B10 | |
| Water SCHEMBL28106109 | 0.70 | PARP1 (0.61) | PARP1KDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL8221166 | 0.70 | PARP1 (0.56) | PARP1KDM4EL3MBTL1ALDH1A1MAPT | |
| SCHEMBL1804352 | 0.70 | PARP1 (0.56) | PARP1KDM4EL3MBTL1ALDH1A1MAPT | |
| SCHEMBL857633 | 0.69 | MAPT (0.34) | PARP1KDM4EALDH1A1MAPTPDGFRA | |
| SCHEMBL4470271 | 0.69 | ALDH1A1 (0.34) | PARP1KDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL5750689 | 0.69 | TRIM24 (0.39) | KDM4EL3MBTL1ALDH1A1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL29266188 | 0.68 | MAPT (0.33) | PARP1KDM4EALDH1A1MAPTPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |