SCHEMBL574716

SCHEMBL574716

O=C(c1ccccc1)c1ccc(OCCO)c(O)c1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.63
KDM4E B2RXH2 5/20 0.63
ALOX15 P16050 4/20 0.63
HSD17B10 Q99714 4/20 0.63
MAPK1 P28482 2/20 0.63
GAA P10253 2/20 0.54
ALDH1A1 P00352 5/20 0.48
RECQL P46063 4/20 0.48
HPGD P15428 3/20 0.48
LMNA P02545 2/20 0.48
CYP3A4 P08684 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CCNE2 O96020 1/20 0.45
CCNE1 P24864 1/20 0.45
CDK2 P24941 1/20 0.45
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
IDO1 P14902 1/20 0.44
DRD2 P14416 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28683507 0.83 MAPT (0.69) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL29415002 0.83 MAPT (0.69) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL27995934 0.83 MAPT (0.61) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL27993046 0.83 MAPT (0.61) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL7850202 0.83 MAPT (0.61) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL8968686 0.82 SELL (0.47) MAPTALDH1A1TDP1IDO1KMT2A
SCHEMBL2228867 0.81 DRD2 (0.62) MAPTKDM4EGAAALDH1A1LMNA
SCHEMBL28384306 0.80 DRD2 (0.49) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL28019921 0.80 THRB (0.55) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL28348202 0.79 MAPT (0.56) MAPTKDM4EALOX15HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
CN-117940496-A Thermoplastic polyurethane foam steering wheel cover 路博润先进材料公司 2024-04-26 CN disclosed
CN-117940472-A Steering wheel structure 路博润先进材料公司 2024-04-26 CN disclosed
CN-103080203-B Stabilized photoactive composition and use thereof ENI SPA 2015-07-22 CN disclosed
EP-2601257-A1 STABILIZED PHOTOACTIVE COMPOSITION AND USE THEREOF ENI S.p.A. (IT) 2013-06-12 EP disclosed
CN-103080203-A Stabilized photoactive composition and use thereof ENI SPA 2013-05-01 CN disclosed
WO-2012017046-A1 STABILIZED PHOTOACTIVE COMPOSITION AND USE THEREOF ENI S.P.A. (IT) 2012-02-09 WO disclosed
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO disclosed