Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745406 | 0.90 | PTGS1 (0.67) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL16209660 | 0.71 | KMT2A (0.78) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL5747229 | 0.71 | KMT2A (0.53) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL5155020 | 0.70 | PTGS1 (0.74) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL3546909 | 0.69 | PTGS1 (0.58) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL5745404 | 0.68 | PTGS2 (0.53) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL8633582 | 0.68 | PTGS1 (0.62) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL2101055 | 0.68 | PTGS1 (0.55) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL3742399 | 0.67 | KCNA5 (1.00) | PTGS1PTGS2GAAKMT2AL3MBTL1 | |
| SCHEMBL5155105 | 0.67 | PTGS1 (0.67) | PTGS1PTGS2GAAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |
| US-6713477-B1 | 1,4-BENZTHIAZINES OR BENZOXAZINES; MATRIX METALLOPROTEINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-30 | — | — | US | disclosed |