SCHEMBL574739

SCHEMBL574739

CSc1nc(NC(=O)[C@@H](N)[C@@H](C)O)c2ncn([C@@H]3O[C@H](COC(N)=O)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 6/20 0.50
P2RY12 Q9H244 3/20 0.50
ENPP1 P22413 3/20 0.50
TARS1 P26639 2/20 0.50
P2RY11 Q96G91 3/20 0.49
BLM P54132 2/20 0.49
LMNA P02545 1/20 0.49
KMT2A Q03164 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
P2RX1 P51575 1/20 0.49
P2RX3 P56373 1/20 0.49
P2RY6 Q15077 1/20 0.49
P2RX4 Q99571 1/20 0.49
PMP22 Q01453 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28894185 0.89 ADORA3 (0.54) CYP2C19
SCHEMBL28894183 0.89 ADORA3 (0.54) CYP2C19
SCHEMBL5155877 0.86 TARS1 (0.62) P2RY12TARS1
SCHEMBL29389281 0.83 ADORA3 (0.51) CYP2C19
SCHEMBL1274809 0.83 ADORA3 (0.51) CYP2C19
SCHEMBL1274810 0.83 ADORA3 (0.51) CYP2C19
SCHEMBL1707366 0.83 ADORA3 (0.51) CYP2C19
SCHEMBL28671612 0.81 ADORA3 (0.52) CYP2C19
SCHEMBL28671616 0.81 ADORA3 (0.52) CYP2C19
SCHEMBL31490447 0.80 KDM4E (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2815 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
US-12503720-B2 Multiplexed profiling of RNA and DNA modifications Alida Biosciences Inc. (US) 2025-12-23 US claimed
US-20250345406-A1 CHIMERIC PROTEINS IN AUTOIMMUNITY SHATTUCK LABS INC (US) 2025-11-13 US claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
US-12338485-B2 Multiplexed profiling of RNA and DNA modifications Alida Biosciences Inc. (US) 2025-06-24 US claimed
WO-2025122721-A1 CHIMERIC PROTEINS AND USES THEREOF SHATTUCK LABS, INC. (US) 2025-06-12 WO claimed
US-12281360-B2 RNA and DNA analysis using engineered surfaces ALIDA BIOSCIENCES, INC. (US) 2025-04-22 US claimed
WO-2025049610-A1 MULTI-ACTION PEPTIDES SHATTUCK LABS, INC. (US) 2025-03-06 WO claimed
US-20250019719-A1 Purification and Purity Assessment of RNA Molecules Synthesized with Modified Nucleosides THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2025-01-16 US claimed
EP-2755693-A2 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF Moderna Therapeutics, Inc. (US) 2014-07-23 EP claimed
EP-2710136-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF FOR NON-HUMAN VERTEBRATES Moderna Therapeutics, Inc. (US) 2014-03-26 EP claimed
EP-2691101-A2 DELIVERY AND FORMULATION OF ENGINEERED NUCLEIC ACIDS Moderna Therapeutics, Inc. (US) 2014-02-05 EP claimed
WO-2013151672-A2 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF ONCOLOGY-RELATED PROTEINS AND PEPTIDES modeRNA Therapeutics (US) 2013-10-10 WO claimed
WO-2013151671-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF COSMETIC PROTEINS AND PEPTIDES modeRNA Therapeutics (US) 2013-10-10 WO claimed
WO-2013151736-A2 IN VIVO PRODUCTION OF PROTEINS modeRNA Therapeutics (US) 2013-10-10 WO claimed
WO-2013039861-A2 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF modeRNA Therapeutics (US) 2013-03-21 WO claimed
WO-2012158736-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF FOR NON-HUMAN VERTEBRATES modeRNA Therapeutics (US) 2012-11-22 WO claimed
WO-2012135805-A2 DELIVERY AND FORMULATION OF ENGINEERED NUCLEIC ACIDS modeRNA Therapeutics (US) 2012-10-04 WO claimed
US-20120251618-A1 DELIVERY AND FORMULATION OF ENGINEERED NUCLEIC ACIDS modeRNA Therapeutics (US) 2012-10-04 US claimed