Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 14/20 | 0.56 |
| ▸ | F13A1 | P00488 | 11/20 | 0.56 |
| ▸ | TGM1 | P22735 | 8/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.49 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252120 | 0.85 | TGM2 (0.63) | TGM2F13A1TGM1GPR119 | |
| SCHEMBL5746429 | 0.84 | TGM2 (0.62) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL7737635 | 0.80 | TGM2 (0.55) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL14696050 | 0.80 | GAA (0.55) | TGM2F13A1TGM1GPR119 | |
| SCHEMBL18410584 | 0.79 | TGM2 (0.65) | TGM2F13A1TGM1PKM | |
| SCHEMBL4573247 | 0.79 | TGM2 (0.54) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL2378015 | 0.79 | TGM2 (0.54) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL5424584 | 0.79 | PKLR (0.56) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL1181678 | 0.79 | MEN1 (0.58) | TGM2F13A1TGM1PKM | |
| SCHEMBL4002418 | 0.79 | TGM2 (0.61) | TGM2F13A1TGM1GPR119TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006120349-A1 | NOVEL PHENYL-PYRIDINYL-PIPERAZINE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | LES LABORATOIRES SERVIER (FR) | 2006-11-16 | — | — | WO | disclosed |
| EP-1721897-A1 | Phenylpyridinylpiperazin derivatives, the process to make them and the pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2006-11-15 | — | — | EP | disclosed |