Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5745752 | 1.00 | MAPT (0.46) | MAPTKDM4EUSP2ALDH1A1GLA | |
| SCHEMBL5746132 | 1.00 | MAPT (0.46) | MAPTKDM4EUSP2ALDH1A1GLA | |
| SCHEMBL5750243 | 0.91 | RORA (0.46) | MAPTKDM4EUSP2ALDH1A1GLA | |
| SCHEMBL5747112 | 0.91 | RORA (0.46) | MAPTKDM4EUSP2ALDH1A1GLA | |
| SCHEMBL5748433 | 0.91 | RORA (0.46) | MAPTKDM4EUSP2ALDH1A1GLA | |
| SCHEMBL31236758 | 0.84 | MAPT (0.50) | MAPTKDM4EALDH1A1CYP3A4GAA | |
| SCHEMBL22288223 | 0.83 | CYP1A2 (0.50) | MAPTKDM4EALDH1A1GLAGAA | |
| SCHEMBL5747932 | 0.82 | PARP1 (0.49) | TLR8HTR2ADRD2SLC6A2HTR2C | |
| SCHEMBL5747036 | 0.82 | PARP1 (0.49) | TLR8HTR2ADRD2SLC6A2HTR2C | |
| SCHEMBL5749210 | 0.82 | PARP1 (0.49) | TLR8HTR2ADRD2SLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |