Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747613 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KDM4ECA1CA2MEN1 | |
| SCHEMBL29391266 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4ECA1CA2MEN1 | |
| SCHEMBL32211 | 0.84 | ALDH1A1 (0.58) | ALDH1A1KDM4ECA1CA2MEN1 | |
| SCHEMBL12679885 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ECA1CA2MEN1 | |
| SCHEMBL5211903 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4ECA1CA2MEN1 | |
| SCHEMBL5751193 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KDM4ECA1CA2MEN1 | |
| SCHEMBL2251091 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL27642965 | 0.74 | ALDH1A1 (0.35) | ALDH1A1KDM4ECA1CA2MEN1 | |
| SCHEMBL2701042 | 0.74 | CYP1A2 (0.41) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL5746118 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4ECA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |