Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | CASP1 | P29466 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | CASP7 | P55210 | 2/20 | 0.61 |
| ▸ | HBB | P68871 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747772 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL14100536 | 0.84 | CYP1A2 (0.63) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL12068359 | 0.84 | CYP1A2 (0.63) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL1309620 | 0.84 | CYP1A2 (0.67) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL890047 | 0.84 | CYP1A2 (0.67) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL5400012 | 0.84 | CYP1A2 (0.67) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL5008739 | 0.82 | ALDH1A1 (0.82) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL5012455 | 0.82 | ALDH1A1 (0.82) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL5012443 | 0.82 | ALDH1A1 (0.82) | ALDH1A1HSD17B10CYP3A4CASP1TDP1 | |
| SCHEMBL130783 | 0.82 | CYP1A2 (0.69) | ALDH1A1HSD17B10CYP3A4TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |