Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767247 | 0.85 | MAPK1 (0.34) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL2783077 | 0.83 | MAPK1 (0.35) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL7359958 | 0.76 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL22152561 | 0.76 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL7379626 | 0.76 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL6588171 | 0.73 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL16915099 | 0.73 | NFKB1 (0.40) | MAPK1NFKB1NFKB2RELA | |
| SCHEMBL4872602 | 0.72 | CYP2D6 (0.37) | — | |
| SCHEMBL248747 | 0.72 | NOS2 (0.39) | — | |
| SCHEMBL248746 | 0.72 | NOS2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900666-A1 | AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C | Ignyta, Inc. (US) | 2015-08-05 | — | — | EP | disclosed |
| WO-2014052699-A9 | AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C | IGNYTA, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| EP-1636217-A1 | 2-IMIDAZO-BENZOTHIAZOLES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101558-A1 | 2-IMIDAZO-BENZOTHIAZOLES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-25 | — | — | WO | disclosed |