Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747767 | 0.92 | ALDH1A1 (0.46) | KDM4EALDH1A1GAAIRAK4IDO1 | |
| SCHEMBL3899987 | 0.83 | IDO1 (0.42) | KDM4EALDH1A1IDO1MAPTTDP1 | |
| SCHEMBL293511 | 0.82 | ALDH1A1 (0.38) | KDM4EALDH1A1GAAIDO1MAPT | |
| SCHEMBL3391383 | 0.77 | HSP90AA1 (0.46) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL3911957 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1GAAIDO1MAPT | |
| SCHEMBL3390191 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1IRAK4MAPTTSHR | |
| SCHEMBL27575531 | 0.72 | HPGD (0.49) | KDM4EALDH1A1GAAMAPTPOLB | |
| Anthracene SCHEMBL28140459 | 0.71 | ALDH1A1 (0.58) | KDM4EALDH1A1GAAIRAK4IDO1 | |
| SCHEMBL1004596 | 0.70 | KDM4E (0.63) | KDM4EALDH1A1GAAIRAK4IDO1 | |
| SCHEMBL5749007 | 0.69 | IKBKB (0.49) | KDM4EALDH1A1GAAHTR3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |