Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA7 | P43166 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391383 | 0.81 | HSP90AA1 (0.46) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL293511 | 0.75 | ALDH1A1 (0.38) | KDM4ELMNAALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5748265 | 0.73 | KDM4E (0.44) | KDM4ELMNAL3MBTL1ALDH1A1CYP2C19 | |
| SCHEMBL3899987 | 0.73 | IDO1 (0.42) | KDM4EALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL130469 | 0.73 | PDCD1 (0.47) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL23997992 | 0.71 | NPC1 (0.64) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL6952994 | 0.71 | CA12 (0.55) | KDM4ELMNAL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL22263726 | 0.71 | KDM4E (0.44) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL6950001 | 0.70 | CA12 (0.53) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL6231650 | 0.70 | CA12 (0.60) | KDM4ELMNATP53L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716160-B1 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-29 | — | — | EP | claimed |
| US-9730449-B2 | Thiazole compound and its use in pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| EP-3093286-A1 | THIAZOLE COMPOUNDS AND PEST CONTROL APPLICATIONS THEREOF | Sumitomo Chemical Co., Ltd (JP) | 2016-11-16 | — | — | EP | disclosed |
| US-20160324155-A1 | THIAZOLE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-11-10 | — | — | US | disclosed |
| EP-1716160-B1 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160324155-A1 | THIAZOLE COMPOUND AND ITS USE IN PEST CONTROL | TRPA1, NAT1, TAS2R1 | KDM4E 2535/4885LMNA 4191/4885TP53 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.