Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 7/20 | 0.44 |
| ▸ | PLAU | P00749 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749126 | 0.87 | LCK (0.53) | LCKPARP1PLAUHSD17B10CYP3A4 | |
| SCHEMBL5748235 | 0.87 | LCK (0.53) | LCKPARP1PLAUHSD17B10CYP3A4 | |
| SCHEMBL5748294 | 0.86 | LCK (0.46) | LCKPARP1PLAUHSD17B10TSHR | |
| SCHEMBL5652182 | 0.84 | PTPN1 (0.47) | HSD17B10TSHRPOLBMAPTTDP1 | |
| SCHEMBL7784887 | 0.82 | MAPT (0.50) | MAPTKDM4EALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL28141360 | 0.78 | PLK1 (0.51) | PLAUTSHRTDP1SMN1; SMN2PSMD14 | |
| SCHEMBL18936010 | 0.78 | ALOX15 (0.51) | LCKPLAUHSD17B10TSHRMAPT | |
| SCHEMBL5751330 | 0.77 | LCK (0.44) | LCKPARP1PLAUROCK2PIM1 | |
| SCHEMBL5748994 | 0.76 | PARP1 (0.43) | LCKPARP1PLAUHSD17B10TSHR | |
| SCHEMBL3242434 | 0.73 | LCK (0.52) | LCKPARP1PLAUROCK2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |