SCHEMBL5652182

SCHEMBL5652182

O=C(O)c1ccc2[c]cccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.47
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA6 P23280 2/20 0.42
CA9 Q16790 2/20 0.42
KDM4E B2RXH2 5/20 0.41
MGAM O43451 1/20 0.40
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CA4 P22748 1/20 0.39
PTGS2 P35354 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6633670 0.85 MEN1 (0.44) PTPN1MEN1KMT2ACA12CA1
SCHEMBL7784887 0.84 MAPT (0.50) MEN1KMT2AKDM4EMAPTCES2
SCHEMBL5748306 0.84 LCK (0.46) KDM4EPOLBMAPTL3MBTL1TSHR
SCHEMBL9115617 0.80 TSHR (0.46) CA12CA1CA2CA6CA9
SCHEMBL28141360 0.80 PLK1 (0.51) TSHRHPGDSMN1; SMN2TDP1
SCHEMBL18936010 0.80 ALOX15 (0.51) MEN1KMT2ACA12CA1CA2
SCHEMBL9776324 0.76 IDO1 (0.44) PTPN1MEN1KMT2ACA12CA1
SCHEMBL5966218 0.76 MEN1 (0.46) PTPN1MEN1KMT2ACA12CA1
SCHEMBL8528700 0.73 DAO (0.33) MEN1KMT2AKDM4EMGAMMAPT
Benzene SCHEMBL27872998 0.73 KDM4E (0.65) PTPN1MEN1KMT2ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5281263-A Disazo dyes for inks printed paper IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-25 US claimed
CN-106572659-A Noxious arthropod control agent containing amide compound 住友化学株式会社 2017-04-19 CN disclosed
US-20060257917-A1 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS MILLIPORE CORPORATION 2006-11-16 US disclosed
US-7122299-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2006-10-17 US disclosed
US-7091348-B2 Fluorescent dyes, energy transfer couples and methods GUAVA TECHNOLOGIES, INC. (US) 2006-08-15 US disclosed
EP-1539728-A2 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS Guava Technologies, Inc. (US) 2005-06-15 EP disclosed
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
US-20040185392-A1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. 2004-09-23 US disclosed
EP-1441013-A1 WATERCOLOR INK Mitsui Chemicals, Inc. (JP) 2004-07-28 EP disclosed
US-20040073014-A1 Fluorescent dyes, energy transfer couples and methods EMD MILLIPORE CORPORATION 2004-04-15 US disclosed
US-5756693-A BLACK COLORANT FOR INK JET PRINTING ZENECA LIMITED (DE) 1998-05-26 US disclosed
EP-0840766-A1 STABILISED DYE COMPOSITION ZENECA LIMITED (GB) 1998-05-13 EP disclosed
EP-0759956-A1 DISAZO COMPOUND ZENECA LIMITED (GB) 1997-03-05 EP disclosed
WO-1997003132-A1 STABILISED DYE COMPOSITION ZENECA LIMITED (GB) 1997-01-30 WO disclosed
EP-0572419-B1 ANIONIC DISAZO DYES ZENECA LTD (GB) 1996-11-13 EP disclosed
WO-1996013553-A1 DISARO COLORANT ZENECA LIMITED (GB) 1996-05-09 WO disclosed
WO-1995031505-A1 DISAZO COMPOUND ZENECA LIMITED (GB) 1995-11-23 WO disclosed
US-5281263-A Disazo dyes for inks printed paper IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-25 US disclosed
EP-0572419-A1 ANIONIC DISAZO DYES. ZENECA LTD (GB) 1993-12-08 EP disclosed
WO-1992013037-A1 ANIONIC DISAZO DYES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060257917-A1 FLUORESCENT DYES, ENERGY TRANSFER COUPLES AND METHODS TIMM50, TIMM44, APEX1 PTPN1 4848/4885MEN1 2623/4885KMT2A 3600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.